The management of epilepsy is difficult due to the complexity of the causes of seizures and the diverse, yet highly personal nature, of seizure expression. NIESM is focusing in closing the loop such that better care and improved health and quality of life outcomes can be more effectively and rapidly achieved. NIESM establishes medical innovations that will advance the management of epilepsy and help patients to become seizure free. It is using a variety of hardware devices and a powerful enterprise software system that will change the management of epilepsy to provide better global outcomes. NIESM, a Melbourne-based Australian company, has built a global team with world leaders in technology, clinical and business capabilities. NIESM is establishing sites in the UK (it's first market), Portugal, India and Singapore (market and development center).